{"id":388,"date":"2018-06-10T12:10:17","date_gmt":"2018-06-10T04:10:17","guid":{"rendered":"http:\/\/tre.tech.blog\/2018\/06\/10\/omega-3-%e8%84%82%e8%82%aa%e9%85%b8%e7%9a%84%e4%bb%a3%e8%ac%9d%e4%b9%9f%e6%98%af%e8%ac%9b%e5%a4%a9%e4%bb%bd%e7%9a%84%ef%bc%81%e4%bd%a0%e5%92%8c%e5%9b%a0%e6%89%ad%e7%89%b9%e4%ba%ba%e8%aa%b0%e6%af%94\/"},"modified":"2018-06-10T12:10:17","modified_gmt":"2018-06-10T04:10:17","slug":"omega3-transform-efficiency-genetics","status":"publish","type":"post","link":"https:\/\/nutrinote.co\/omega3-transform-efficiency-genetics\/","title":{"rendered":"Omega3 \u8102\u80aa\u9178\u7684\u4ee3\u8b1d\u4e5f\u662f\u8b1b\u5929\u4efd\u7684\uff01"},"content":{"rendered":"\n<blockquote class=\"wp-block-quote is-style-large is-layout-flow wp-block-quote-is-layout-flow\"><p>\u4f60\u548c\u56e0\u626d\u7279\u4eba\u8ab0\u6bd4\u8f03\u9700\u8981\u5403\u9b5a\u6cb9\uff1f<\/p><\/blockquote>\n\n\n<p>\u4e0d\u7ba1\u662f\u81ea\u5df1\u4ee5\u524d\u5728\u7576\u4fdd\u5065\u98df\u54c1\u539f\u6599\u7684 PM \u9084\u662f\u770b\u5230\u9b5a\u6cb9\u76f8\u95dc\u7684\u8cc7\u6599\uff0c\u7e3d\u662f\u6703\u5f37\u8abf EPA\/DHA \u7684\u91cd\u8981\u6027\uff0c\u4e26\u8aaa\u4f86\u81ea\u690d\u7269\u7684 \u03b1-\u6b21\u4e9e\u9ebb\u6cb9\u9178\uff08\u03b1-Linolenic acid\uff0c\u7e2e\u5beb ALA\uff09\u7684\u8f49\u63db\u6210 EPA \u8207 DHA \u7684\u6548\u7387\u4e0d\u597d\uff0c\u76f4\u63a5\u88dc\u5145\u624d\u6703\u5920\u3002\u90a3\u6642\u9084\u5e38\u6703\u807d\u805e\u300c\u4f4f\u5728\u5317\u6975\u5708\u7684\u56e0\u7d10\u7279\u4eba\u5c31\u662f\u5403\u5f88\u591a\u9b5a\u624d\u6c92\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u300d\u7684\u8aaa\u6cd5\u3002<\/p>\n\n\n<p>\u4f46\u7e3d\u89ba\u5f97\u54ea\u908a\u602a\u602a\u7684\uff0c\u4e8b\u60c5\u6709\u9019\u9ebc\u55ae\u7d14\u55ce\uff1f\u4f60\u60f3\u60f3\u770b\u5594\uff0c\u5728\u904e\u53bb\u904b\u8f38\u4fdd\u5b58\u6280\u8853\u4e0d\u767c\u9054\u7684\u5e74\u4ee3\uff0c\u90a3\u4e9b\u4f4f\u5728\u5c71\u4e0a\u6216\u5167\u9678\u5730\u5340\u7684\u4eba\uff0c\u9084\u6709\u98f2\u98df\u4ee5\u690d\u7269\u4f86\u6e90\u4e3b\u7684\u4eba\u5011\uff0c\u9019\u4e9b\u4eba\u5176\u5be6\u6c92\u4ec0\u9ebc\u6a5f\u6703\u5403\u5230\u5bcc\u542b EPA \u548c DHA \u7684\u9b5a\uff0c\u4f46\u4eba\u5bb6\u9084\u4e0d\u662f\u4e00\u76f4\u6d3b\u5f97\u597d\u597d\u7684\uff1f<\/p>\n\n\n<p>\u5f8c\u4f86\u5728\u300c\u76f2\u773c\u7684\u5c3c\u5b89\u5fb7\u5854\u77f3\u5668\u5320\u300d\u770b\u5230\u4eba\u985e\u8102\u80aa\u9178\u53bb\u98fd\u548c\u9176\u6703\u53d7\u74b0\u5883\u9078\u6c70\u7684\u6587\u7ae0\u5f8c\uff0c\u55ef\uff0c\u9019\u6216\u8a31\u662f\u500b\u597d\u65b9\u5411\u5594\uff01<\/p>\n\n\n<h2 id=\"%e5%bf%85%e9%9c%80%e8%84%82%e8%82%aa%e9%85%b8%e3%80%81omega3-%e5%92%8c-omega6-%e6%98%af%e4%bb%80%e9%ba%bc%e6%84%8f%e6%80%9d\" class=\"wp-block-heading\">\u5fc5\u9700\u8102\u80aa\u9178\u3001Omega3 \u548c Omega6&nbsp;\u662f\u4ec0\u9ebc\u610f\u601d<\/h2>\n\n\n<p>\u5728\u9032\u5165\u6b63\u984c\u524d\uff0c\u9084\u662f\u8981\u5148\u804a\u4e00\u4e0b\u4ec0\u9ebc\u662f\u300c<strong>\u5fc5\u9700\u8102\u80aa\u9178<\/strong>\u300d\u3002\u4e00\u822c\u4eba\u6210\u9577\u5230\u4e00\u5b9a\u968e\u6bb5\u5f8c\uff0c\u6703\u6709\u5169\u500b\u5fc5\u9700\u8102\u80aa\u9178\uff0c\u5206\u5225\u662f <strong>Omega-6 \u7684\u4e9e\u6cb9\u9178\uff08Linoleic acid\uff0cLA\uff09<\/strong>\u8207<strong> Omega3 \u7684 ALA<\/strong>\uff0c\u7531\u65bc\u4eba\u985e\u7684\u7d30\u80de\u6c92\u8fa6\u6cd5\u505a\u51fa Omega3\/6 \u57fa\u672c\u67b6\u69cb\u7684\u95dc\u4fc2\uff0c\u5c31\u5f97\u5f9e\u5916\u5728\u7684\u74b0\u5883\u7372\u53d6\u5566\u3002<\/p>\n\n\n<p>\u7e3d\u662f\u807d\u4eba\u8b1b Omega \u5e7e\u7684\uff0c\u90a3\u5230\u5e95 Omega \u662f\u4ec0\u9ebc\u610f\u601d\u5462\uff1f \u5b83\u662f\u4e00\u7a2e\u8868\u793a\u8102\u80aa\u9178\u93c8\u4e0a\u7684\u4f4d\u7f6e\uff0c\u4ee5\u7b2c\u4e00\u500b\u78b3\uff08CH3 \u90a3\u7aef\uff09\u958b\u59cb\u6578\uff0cOmega3 \u7684\u610f\u601d\u5c31\u662f\u5f9e\u7b2c\u4e00\u500b\u78b3\u958b\u59cb\u6578\u7684\u7b2c\u4e09\u500b\u78b3\u4e0a\u6709\u96d9\u9375\uff0c\u770b\u6587\u5b57\u53ef\u80fd\u6bd4\u8f03\u96e3\u60f3\u50cf\uff0c\u8acb\u770b\u4e0b\u5716\u7684\u4f8b\u5b50\u5427\u3002<\/p>\n\n\n<figure class=\"wp-block-image wp-caption\"><img  decoding=\"async\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  alt=\"omega3-\u8102\u80aa\u9178-\u7d50\u69cb\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/cdn-images-1.medium.com\/max\/1200\/1*cM1uFGFT3tf2ov-uf5kh3A.jpeg\" ><figcaption>\u8cc7\u6599\u4f86\u6e90\uff1aWikipedia<\/figcaption><\/figure>\n\n\n<p>\u6709\u4e86 LA \u8207 ALA\uff0c\u5c31\u80fd\u5920\u5408\u6210\u82b1\u751f\u56db\u70ef\u9178\uff08Arachidonic acid\uff0cAA\uff09\u3001EPA \u548c DHA&nbsp;\u2026 \u7b49\u9577\u5ea6\u66f4\u9577\u3001\u96d9\u9375\u66f4\u591a\u7684<strong>\u9577\u93c8\u591a\u5143\u4e0d\u98fd\u548c\u8102\u80aa\u9178\uff08 long chain polyunsaturated acids\uff0cLC-PUFAs\uff09<\/strong>\uff0c\u5c31\u7b97\u98f2\u98df\u4e2d\u5f88\u5c11\u651d\u53d6\u5230\u542b\u6709 AA\u3001EPA \u6216 DHA \u7684\u98df\u7269\uff0c\u8eab\u9ad4\u5c31\u6709\u8fa6\u6cd5\u81ea\u5df1\u505a\u51fa\u4f86\u3002<\/p>\n\n\n<p>\u50cf\u662f\u78f7\u8102\u8cea\u88e1\u8102\u80aa\u9178\u7684\u6bd4\u4f8b\u6703\u6539\u8b8a\u7d30\u80de\u819c\u7684\u6d41\u52d5\u6027\uff0c\u53ef\u80fd\u5f71\u97ff\u7d30\u80de\u819c\u5c0d\u8a0a\u606f\u7684\u63a5\u53d7\uff0c\u4e4b\u524d\u6709\u63d0\u904e\u7d30\u80de\u819c\u6d41\u52d5\u6027\u5dee\u53ef\u80fd\u6703\u5f71\u97ff\u80f0\u5cf6\u7d20\u7684\u4f5c\u7528\u3002<\/p>\n\n\n<p>\u5728\u5206\u5b50\u5c64\u7d1a\u7576\u4e2d\uff0cLC-PUFAs \u9084\u80fd\u767c\u63ee\u597d\u5e7e\u7a2e\u5176\u4ed6\u91cd\u8981\u7684\u529f\u80fd\uff0c\u4f8b\u5982\u5728\u7d30\u80de\u5167\u7684\u8a0a\u606f\u9014\u5f91\u7576\u4e2d\u4f5c\u70ba\u7b2c\u4e8c\u8a0a\u606f\u8005\uff0c\u6216\u8005\u8abf\u7bc0\u8f49\u8b6f\u3002\u6b64\u5916\uff0cLC-PUFAs \u4e5f\u662f<strong>\u985e\u4e8c\u5341\u78b3\u9178<\/strong>\u7684\u524d\u8ec0\u7269\uff08\u767d\u4e09\u70ef\u7d20\u8207\u524d\u5217\u817a\u7d20\uff09\uff0c\u8207\u767c\u708e\u53cd\u61c9\u7684\u767c\u751f\u8207\u6d88\u9664\u6709\u5bc6\u5207\u7684\u95dc\u4fc2\u3002<\/p>\n\n\n<p>\u4e0b\u5716\u7c21\u7565\u5448\u73fe\u51fa LA \u8207 ALA \u5728\u4eba\u9ad4\u5167\u8b8a\u6210 AA\u3001EPA \u8207 DHA \u7684\u8def\u5f91\uff0c\u4ee5\u53ca\u4eba\u5011\u4e3b\u8981\u7372\u53d6\u7684\u98df\u7269\u4f86\u6e90\u3002\u9019\u88e1\u7684\u4e3b\u8981\u4e0d\u662f\u8aaa\u53ea\u6709\u9019\u985e\u7684\u98df\u7269\u624d\u6709\uff0c\u800c\u662f\u5728\u98f2\u98df\u4f86\u6e90\u4e2d\u4f54\u6bd4\u8f03\u591a\uff0c\u5176\u4ed6\u4f86\u6e90\u7684\u98df\u7269\u4e5f\u53ef\u80fd\u542b\u6709\u9019\u4e9b\u8102\u80aa\u9178\uff0c\u4f8b\u5982\u725b\u8089\u4e5f\u662f\u6703\u6709 EPA \u8207 DHA\uff0c\u53ea\u662f\u76f8\u5c0d\u542b\u91cf\u6bd4\u8f03\u5c11\u800c\u5df2\u3002<\/p>\n\n\n<figure class=\"wp-block-image\"><img  decoding=\"async\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  alt=\"\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/cdn-images-1.medium.com\/max\/800\/1*OHk1y9-LFnb08a_pq71m4g.jpeg\" ><\/figure>\n\n\n<p>\u5728\u7c89\u7d05\u8207\u6de1\u85cd\u8272\u7684\u8272\u584a\u4e2d\u9593\uff0c\u6709 FADS1 \u8207 FADS2\uff0c\u5b83\u5011\u662f\u8102\u80aa\u9178\u53bb\u98fd\u548c\u9176\uff08fatty acid desaturase\uff091 \u8207 2\uff0cFADS2 \u80fd\u8b93 18 \u78b3\u8207 24 \u78b3\u8102\u80aa\u9178\u7684\u78b3\u93c8\u4e0a\u589e\u52a0\u4e00\u500b\u96d9\u9375\uff0c\u800c FADS1 \u5247\u662f\u5e6b 20 \u78b3\u7684 Omeg-3\/6 \u589e\u52a0\u4e00\u500b\u96d9\u9375\uff0c\u8b8a\u6210\u82b1\u751f\u56db\u70ef\u9178\u8207 EPA\u3002\uff08\u9084\u6709 FADS3\uff0c\u4e0d\u904e\u73fe\u5728\u9084\u4e0d\u6e05\u695a\u5b83\u7684\u4f5c\u7528\u662f\u4ec0\u9ebc\u3002\uff09<\/p>\n\n\n<h3 id=\"%e9%a3%b2%e9%a3%9f%e8%ae%8a%e9%81%b7%e8%88%87%e5%bf%85%e9%9c%80%e8%84%82%e8%82%aa%e9%85%b8%e7%9a%84%e4%bb%a3%e8%ac%9d%e9%81%a9%e6%87%89\" class=\"wp-block-heading\">\u98f2\u98df\u8b8a\u9077\u8207\u5fc5\u9700\u8102\u80aa\u9178\u7684\u4ee3\u8b1d\u9069\u61c9<\/h3>\n\n\n<p>\u4eba\u985e\u7684\u98f2\u98df\u751f\u6d3b\u4e26\u4e0d\u662f\u4e00\u6210\u4e0d\u8b8a\uff0c\u5f9e\u63a1\u96c6\u72e9\u7375\u3001\u8fb2\u696d\u5230\u73fe\u4ee3\uff0c\u4e0d\u7ba1\u662f\u98df\u7269\u7684\u4f86\u6e90\u3001\u71df\u990a\u7d20\u7684\u6bd4\u4f8b\u9084\u662f\u5f62\u5f0f\u90fd\u6709\u5f88\u5927\u7684\u4e0d\u540c\uff0c\u70ba\u9069\u61c9\u4e0d\u540c\u6642\u671f\u7684\u98f2\u98df\uff0c\u8eab\u9ad4\u6703\u8ddf\u8457\u6f14\u5316\u6210\u9069\u5408\u8a72\u74b0\u5883\u7684\u6a23\u5b50\uff0c\u4f8b\u5982\u5728\u553e\u6db2\u6fb1\u7c89\u9176\u7684\u6587\u7ae0\u88e1\u63d0\u5230\u9032\u5165\u8fb2\u696d\u6642\u4ee3\u7684\u65cf\u7fa4\uff0c\u53ef\u80fd\u56e0\u9577\u671f\u651d\u53d6\u8f03\u591a\u7684\u6fb1\u7c89\u98df\u7269\uff0c\u553e\u6db2\u6fb1\u7c89\u9176\u57fa\u56e0\uff08AMY1\uff09\u4ee5\u589e\u52a0\u62f7\u8c9d\u6578\u7684\u65b9\u5f0f\u4f86\u5f37\u5316\u5c0d\u9019\u985e\u98df\u7269\u7684\u6d88\u5316\u80fd\u529b\uff0c\u53cd\u4e4b\uff0c\u7dad\u6301\u63a1\u96c6\u72e9\u7375\u7684\u65cf\u7fa4\u56e0\u70ba\u98f2\u98df\u7576\u4e2d\u6c92\u6709\u8655\u7406\u90a3\u9ebc\u591a\u6fb1\u7c89\u98df\u7269\u7684\u9700\u6c42\uff0cAMY1 \u7684\u62f7\u8c9d\u6578\u5c31\u53ef\u80fd\u4e0d\u9700\u8981\u90a3\u9ebc\u591a\u500b\u3002<\/p>\n\n\n<p>\u7136\u800c\uff0c\u5f9e\u63a1\u96c6\u72e9\u7375\u8f49\u8b8a\u5230\u8fb2\u696d\u6642\u4ee3\u7684\u98f2\u98df\u8b8a\u5316\u53ef\u4e0d\u50c5\u6b62\u65bc\u5403\u6bd4\u8f03\u591a\u6fb1\u7c89\u800c\u5df2\uff0c\u591a\u5143\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u7684\u5206\u4f48\u4e5f\u8ddf\u8457\u8b8a\u52d5\uff0c\u539f\u672c<strong>\u52d5\u7269\u6216\u6d77\u6d0b\u4f86\u6e90\u98df\u7269\u7684 AA \u8207 EPA \u542b\u91cf\u6bd4\u8f03\u9ad8<\/strong>\uff0c\u8b8a\u6210\u4ee5<strong>\u690d\u7269\u4f86\u6e90\u98df\u7269\u70ba\u4e3b\u7684\u6642\u5019\uff0c\u5c31\u8b8a\u6210 LA \u8207 ALA \u5403\u6bd4\u8f03\u591a<\/strong>\u3002\u672c\u4f86\u4e0d\u7528\u592a\u52aa\u529b\u5408\u6210 AA \u8207 EPA\uff0c\u4f46\u98f2\u98df\u6539\u8b8a\u4e4b\u5f8c\uff0c\u70ba\u4e86\u7dad\u6301\u8ddf\u904e\u53bb\u4e00\u6a23\u7684\u91cf\uff0c\u5c31\u5f97\u5f9e LA \u548c ALA \u4f86\u88fd\u9020\u5566\u3002<\/p>\n\n\n<p><strong>\u8102\u80aa\u9178\u53bb\u98fd\u548c\u9176\uff08FADS1 \u8207 2\uff09\u662f\u5fc5\u9700\u8102\u80aa\u9178\u4ee3\u8b1d\u4e2d\u7684\u95dc\u9375\u9175\u7d20<\/strong>\uff0c\u7814\u7a76\u767c\u73fe\u7de8\u78bc\u9019\u4e9b\u9175\u7d20\u7684\u57fa\u56e0\u5728\u4e0d\u540c\u7684\u65cf\u7fa4\u4e0a\u6703\u6709\u4e9b\u4e0d\u540c\uff0c\u548c\u553e\u6db2\u6fb1\u7c89\u9176\u591a\u62f7\u8c9d\u5e7e\u4efd AMY1 \u7684\u57fa\u56e0\u4e0d\u540c\uff0cFADS \u7684\u8b8a\u5316\u662f\u67d0\u4e9b\u7b49\u4f4d\u57fa\u56e0\u4e0a\u7684\u55ae\u4e00\u9e7c\u57fa\u51fa\u73fe\u4e86\u8b8a\u5316\uff0c\u4e5f\u5c31\u662f\u55ae\u6838\u82f7\u9178\u591a\u614b\u6027\uff08<a href=\"https:\/\/www.wikiwand.com\/zh-tw\/%E5%96%AE%E6%A0%B8%E8%8B%B7%E9%85%B8%E5%A4%9A%E6%85%8B%E6%80%A7\" target=\"_blank\" rel=\"noopener noreferrer\">Single Nucleotide Polymorphism<\/a>\uff0c\u7c21\u7a31 SNP\uff09\uff0c\u8b93 FDAS \u7684\u9175\u7d20\u6d3b\u6027\u767c\u751f\u6539\u8b8a\uff0c\u4f8b\u5982\u662f T \u8b8a C \uff0c\u7814\u7a76\u767c\u73fe FADS1 \u7684 rs174546 \u4f4d\u7f6e\u4e0a\u7684\u591a\u6a23\u6027\u6703\u5f71\u97ff\u5c0d\u651d\u53d6\u8102\u80aa\u9178\u5f8c\uff0c\u8840\u6db2\u5faa\u74b0\u4e2d AA\u3001EPA \u8207 DHA \u7684\u6bd4\u4f8b\u3002<\/p>\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><em>rs174546 \u662f\u4ec0\u9ebc\uff1f \u9019\u7a2e\u7de8\u78bc\u65b9\u5f0f\u7a31\u70ba\u300cRs Numbers\uff0cRsid\u300d\u662f\u7528\u4f86\u8a3b\u8a18\u7279\u5b9a SNPs \u7684\u4f4d\u7f6e\u3002<\/em><\/p><\/blockquote>\n\n\n<p>\u5982\u679c\u4f60\u60f3\u66f4\u4e86\u89e3\u95dc\u65bc FADS1 \u8207 2 \u57fa\u56e0\u7684\u8b8a\u5316\uff0c\u63a8\u85a6\u4f60\u95b1\u8b80\u76f2\u773c\u7684\u5c3c\u5b89\u5fb7\u5854\u77f3\u5668\u5320\u7684\u6587\u7ae0\uff1a<\/p>\n\n\n<p>1. Gene Online\u200a\u2014\u200a<a href=\"https:\/\/geneonline.news\/index.php\/2017\/06\/03\/life-of-dha-and-epa-part-1\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u6cb9\u8102\u4eba\u751f\uff08\u4e0a\uff09\uff1a\u4e0d\u53ef\u6216\u7f3a\u7684\u53bb\u98fd\u548c\u9176<\/a><br \/>&nbsp;2. Gene Online\u200a\u2014\u200a<a href=\"https:\/\/geneonline.news\/index.php\/2017\/06\/05\/life-of-dha-and-epa-part-2\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u6cb9\u8102\u4eba\u751f\uff08\u4e0b\uff09\uff1a\u5343\u8b8a\u842c\u5316\uff0c\u5c62\u53d7\u9078\u6c70\u7684\u53bb\u98fd\u548c\u9176<\/a><\/p>\n\n\n<h3 id=\"fads1-%e5%a4%9a%e6%a8%a3%e6%80%a7%e8%88%87%e9%a3%b2%e9%a3%9f-pufas-%e6%94%9d%e5%8f%96%e5%b0%8d%e5%be%aa%e7%92%b0%e8%84%82%e8%82%aa%e9%85%b8%e6%af%94%e4%be%8b%e7%9a%84%e5%bd%b1%e9%9f%bf\" class=\"wp-block-heading\">FADS1 \u591a\u6a23\u6027\u8207\u98f2\u98df PUFAs \u651d\u53d6\u5c0d\u5faa\u74b0\u8102\u80aa\u9178\u6bd4\u4f8b\u7684\u5f71\u97ff<\/h3>\n\n\n<p>\u4e5f\u56e0\u70ba\u5c0d FADS1 \u7684\u4e86\u89e3\uff0c2018 \u5e74\u6709\u7bc7\u7814\u7a76\u5c31\u53bb\u770b FADS1 \u7684\u57fa\u56e0\u3001\u98f2\u98df\u8102\u80aa\u9178\u651d\u53d6\u4ee5\u53ca\u8840\u4e2d\u8102\u80aa\u9178\u5206\u4f48\u4e4b\u9593\u7684\u95dc\u4fc2\u3002\u7814\u7a76\u767c\u8868\u5728\u300a\u7f8e\u570b\u81e8\u5e8a\u71df\u990a\u5b78\u671f\u520a\u300b\u4e0a\uff0c\u7814\u7a76\u8005\u5f9e Nurses\u2019 Health Study \u548c Health Professionals Follow-Up Study \u53d6\u5f97 2,288 \u4f4d\u53d7\u8a66\u8005\u7684\u8cc7\u6599\uff0c\u5305\u542b\u8840\u6db2\u6a23\u672c\u3001\u534a\u5b9a\u91cf\u98df\u7269\u983b\u7387\u554f\u5377\u4ee5\u53ca FADS1 \u7684\u5b9a\u5e8f\u3002<\/p>\n\n\n<p>\u6700\u5f8c\u767c\u73fe FADS1 rs174546 \u7684\u7b49\u4f4d\u57fa\u56e0\u662f C \u7684\u4eba\uff0c\u8840\u4e2d\u6709\u8f03\u9ad8\u6bd4\u4f8b\u7684 AA\u3001EPA \u8207 DHA\uff0c\u4e14\u8f03\u4f4e\u6bd4\u4f8b\u7684 LA \u8207 ALA\uff0c\u63db\u8a00\u4e4b\uff0c<strong>\u7b49\u4f4d\u57fa\u56e0\u662f T \u7684\u4eba\u5f97\u5f9e\u98f2\u98df\u591a\u651d\u53d6 AA\u3001EPA \u8207 DHA\uff0c\u8840\u4e2d\u9019\u4e9b\u8102\u80aa\u9178\u7684\u6fc3\u5ea6\u624d\u80fd\u548c C \u7b49\u4f4d\u57fa\u56e0\u7684\u4eba\u76f8\u7576<\/strong>\u3002\u63db\u53e5\u8a71\u8aaa FADS1 rs174546 \u4e0a\u5e36\u6709 T \u7684\u4eba\u80fd\u5728\u98df\u7269\u5bcc\u542b AA\u3001EPA \u8207 DHA \u7684\u74b0\u5883\u4e0b\u6d3b\u5f97\u597d\uff0c\u53cd\u4e4b\uff0c\u5e36\u6709 C \u7684\u4eba\u5c31\u7b97\u5728\u98df\u7269\u5bcc\u542b LA \u8207 ALA \u7684\u74b0\u5883\u4e5f\u80fd\u6d3b\u5f97\u5f88\u597d\u3002<\/p>\n\n\n<p>\u5f9e\u9019\u500b\u7d50\u679c\u884d\u4f38\u51fa\u4f86\u7684\u554f\u984c\u5c31\u662f\u9b5a\u6cb9\u9019\u985e\u5bcc\u542b EPA \u8207 DHA \u88dc\u5145\u54c1\u7684\u9069\u7528\u5c0d\u8c61\uff0c\u6216\u8a31\u5148\u4e86\u89e3\u500b\u4eba\u7684\u57fa\u56e0\u518d\u505a\u5efa\u8b70\u53ef\u80fd\u6703\u6bd4\u8f03\u5951\u5408\u9700\u8981\u3002<\/p>\n\n\n<p>25 \u5e74\u524d\u4e0a\u6f14\u7684<strong>\u4f8f\u7f85\u7d00\u516c\u5712<\/strong>\u6709\u53e5\u7d93\u5178\u7684\u53f0\u8a5e\uff1a<strong>\u751f\u547d\u6703\u627e\u5230\u51fa\u8def<\/strong>\uff08Life finds a way.\uff09\u3002<br \/>&nbsp;\u5728\u770b\u904e\u5e7e\u7bc7\u6f14\u5316\u8207\u71df\u990a\u76f8\u95dc\u7684\u7814\u7a76\u4e4b\u5f8c\uff0c\u5fcd\u4e0d\u4f4f\u89ba\u5f97&nbsp;\u2026 \u90a3\u53f0\u8a5e\u5f88\u8cbc\u5207\u5440\uff01<\/p>\n\n\n<p>PS\uff1a\u5c0d\u65bc\u57fa\u56e0\u9084\u6709\u6f14\u5316\u7684\u77e5\u8b58\uff0c\u6211\u9084\u5728\u5b78\u7fd2\u4e2d\uff0c\u5982\u679c\u6709\u932f\u8aa4\u7684\u5730\u65b9\u6216\u7406\u89e3\u932f\u8aa4\u7684\u5730\u65b9\uff0c\u8acb\u7d66\u5e2d\u5c3c\u89aa\u5207\u7684\u6307\u6559\u4e00\u4e0b\u3002<\/p>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h4 id=\"%e5%8f%83%e8%80%83%e6%96%87%e7%8d%bb\" class=\"wp-block-heading\">\u53c3\u8003\u6587\u737b<\/h4>\n\n\n<ol><li>Lattka, E., Illig, T., Heinrich, J., &amp; Koletzko, B. (2009). FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases. Journal of nutrigenetics and nutrigenomics, 2(3), 119\u2013128.<\/li><li>Buckley, M. T., Racimo, F., Allentoft, M. E., Jensen, M. K., Jonsson, A., Huang, H.,&nbsp;\u2026 &amp; J\u00f8rgensen, M. E. (2017). Selection in Europeans on fatty acid desaturases associated with dietary changes. Molecular biology and evolution, 34(6), 1307\u20131318.<\/li><li>Juan, J., Huang, H., Jiang, X., Ardisson Korat, A. V., Song, M., Sun, Q.,&nbsp;\u2026 &amp; Kraft, P. (2018). Joint effects of fatty acid desaturase 1 polymorphisms and dietary polyunsaturated fatty acid intake on circulating fatty acid proportions. The American journal of clinical nutrition, 107(5), 826\u2013833.<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u4f60\u548c\u56e0\u626d\u7279\u4eba\u8ab0\u6bd4\u8f03\u9700\u8981\u5403\u9b5a\u6cb9\uff1f \u4e0d\u7ba1\u662f\u81ea\u5df1\u4ee5\u524d\u5728\u7576\u4fdd\u5065\u98df\u54c1\u539f&hellip;<\/p>\n","protected":false},"author":2,"featured_media":1298,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[77,119],"tags":[146,54,86,2],"powerkit_post_featured":[],"_links":{"self":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/388"}],"collection":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/comments?post=388"}],"version-history":[{"count":0,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/388\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/media\/1298"}],"wp:attachment":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/media?parent=388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/categories?post=388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/tags?post=388"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/powerkit_post_featured?post=388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}