{"id":345,"date":"2017-04-13T12:09:43","date_gmt":"2017-04-13T04:09:43","guid":{"rendered":"http:\/\/tre.tech.blog\/2017\/04\/13\/%e6%83%b3%e9%a0%90%e9%98%b2%e9%98%bf%e8%8c%b2%e6%b5%b7%e9%bb%98%e7%97%87\/"},"modified":"2017-04-13T12:09:43","modified_gmt":"2017-04-13T04:09:43","slug":"prevent-ad-good-sleep-quality-key","status":"publish","type":"post","link":"https:\/\/nutrinote.co\/prevent-ad-good-sleep-quality-key\/","title":{"rendered":"\u60f3\u9810\u9632\u963f\u8332\u6d77\u9ed8\u75c7\uff1f \u7761\u5f97\u597d\u662f\u57fa\u672c\u5c0d\u7b56"},"content":{"rendered":"\n<p>\u4eba\u7684\u4e00\u751f\u6709\u4e09\u5206\u4e4b\u4e00\u7684\u6642\u9593\u5728\u7761\u89ba\uff0c\u6216\u8a31\u6703\u6709\u4eba\u89ba\u5f97\u597d\u6d6a\u8cbb\u5594\uff01\u60f3\u8aaa\u5728\u6709\u9650\u4eba\u751f\u88e1\u982d\uff0c\u537b\u5f97\u7528\u6389\u90a3\u9ebc\u591a\u7684\u6642\u9593\uff0c\u62ff\u4f86\u6253\u62fc\u6216\u662f\u73a9\u6a02\u4e0d\u662f\u6bd4\u8f03\u597d\uff1f<\/p>\n\n\n<p>\u7136\u800c\uff0c\u4e0d\u7ba1\u662f\u4ec0\u9ebc\u6a23\u7684\u751f\u7269\uff0c\u4eca\u5929\u6703\u9577\u9019\u526f\u5fb7\u6027\uff0c\u6216\u662f\u767c\u5c55\u51fa\u67d0\u7a2e\u884c\u70ba\u53ef\u662f\u7d93\u904e\u76f8\u7576\u6f2b\u9577\u7684\u6b72\u6708\u6f14\u5316\u800c\u4f86\uff0c\u4e0d\u70ba\u5225\u7684\uff0c\u5c31\u53ea\u662f\u60f3\u8981\u6d3b\u4e0b\u53bb\u3002\u7761\u7720\u4e5f\u662f\u5982\u6b64\uff0c\u5b83\u7684\u5b58\u5728\u662f\u6709\u610f\u7fa9\u7684\u5440\u3002<\/p>\n\n\n<p>\u4e4b\u524d\u5728 TED \u4e0a\u66fe\u770b\u5230\u4e00\u500b\u8b1b\u7761\u7720\u8207\u8166\u90e8\u5ee2\u68c4\u7269\u4ee3\u8b1d\u7684\u6f14\u8b1b\uff0c\u5c31\u8ddf\u4eca\u5929\u8981\u5206\u4eab\u7684\u65b0\u7814\u7a76\u6709\u95dc\u3002\u5f71\u7247\u5927\u62b5\u4e0a\u662f\u8aaa\u4eba\u5728\u7761\u89ba\u7684\u6642\u5019\u5927\u8166\u624d\u6709\u8fa6\u6cd5\u597d\u597d\u7684\u6e05\u9664\u6e05\u9192\u6642\u8166\u7d30\u80de\u4ee3\u8b1d\u7522\u51fa\u7684\u5ee2\u7269\uff0c\u4e5f\u5c31\u662f\u8aaa\u5982\u679c\u4eba\u5011\u4e00\u76f4\u90fd\u7761\u7720\u7f3a\u4e4f\uff0c\u9577\u671f\u4e0b\u4f86\u9019\u4e9b\u5ee2\u7269\u7684\u7d2f\u7a4d\u5c31\u53ef\u80fd\u6703\u5f71\u97ff\u8166\u90e8\u7684\u6b63\u5e38\u529f\u80fd\uff0c\u4f8b\u5982\u963f\u8332\u6d77\u9ed8\u75c7\uff08Alzheimer&#8217;s disease\uff0c\u7c21\u7a31 AD\uff09\u7684\u767c\u751f\u5c31\u53ef\u80fd\u548c\u9019\u6709\u95dc\u4fc2\u3002\u6b64\u6f14\u8b1b\u5f88\u503c\u5f97\u4e00\u770b\uff0c\u5efa\u8b70\u4f60\u53ef\u4ee5\u62bd\u500b\u7a7a\u770b\u77a7\u77a7\u3002\uff08\u4e0b\u9762\u7684\u5f71\u7247\u53ef\u4ee5\u5207\u63db\u4e2d\u6587\u5b57\u5e55\uff09<\/p>\n\n\n<p><\/p>\n\n\n<figure class=\"wp-block-embed-ted wp-block-embed is-type-video is-provider-ted wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Jeff Iliff: One more reason to get a good night&#039;s sleep\" src=\"https:\/\/embed.ted.com\/talks\/jeff_iliff_one_more_reason_to_get_a_good_night_s_sleep\" width=\"1160\" height=\"653\" frameborder=\"0\" scrolling=\"no\" webkitAllowFullScreen mozallowfullscreen allowFullScreen><\/iframe>\n<\/div><\/figure>\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h2 id=\"%e7%9d%a1%e7%9c%a0%e5%89%9d%e5%a5%aa%e8%88%87%e6%be%b1%e7%b2%89%e6%a8%a3%e8%9b%8b%e7%99%bd%e7%9a%84%e7%a0%94%e7%a9%b6\" class=\"wp-block-heading\">\u7761\u7720\u525d\u596a\u8207\u6fb1\u7c89\u6a23\u86cb\u767d\u7684\u7814\u7a76<\/h2>\n\n\n<p>\u6700\u8fd1\u770b\u5230\u4e00\u7bc7\u65b0\u7684\u7814\u7a76\uff0c\u6b63\u597d\u80fd\u8ddf\u4e0a\u982d\u7684\u5f71\u7247\u547c\u61c9\u3002\u8a72\u7814\u7a76\u8a2d\u8a08\u4e86\u4e00\u500b 24 \u5c0f\u6642\u7761\u7720\u525d\u596a\u8a66\u9a57\uff0c\u4e26\u89c0\u5bdf\u671f\u9593\u53c3\u8207\u8005\u5011\u8840\u4e2d\u5404\u7a2e\u751f\u5316\u6307\u6a19\uff0c\u7279\u5225\u662f\u6fb1\u7c89\u6a23\u86cb\u767d\uff08 amyloid-\u03b2, \u7c21\u7a31 A\u03b2\uff09\u7684\u8b8a\u5316\uff0c\u5f9e\u4e2d\u60f3\u77e5\u9053\u4e0d\u7761\u89ba\u7684\u5f71\u97ff\u3002<\/p>\n\n\n<p>\u7814\u7a76\u5728 2016 \u5e74 3\/1 ~ 4 \/1 \u9593\u9032\u884c\u7684\u81e8\u5e8a\u8a66\u9a57\uff0c\u7e3d\u5171\u6709 20 \u4f4d\u8a8d\u77e5\u529f\u80fd\u8207\u7761\u7720\u6b63\u5e38\u7684\u4eba\u53c3\u8207\uff08\u5e73\u5747\u5e74\u9f61 27.3 \u6b72\uff09\u3002\u7814\u7a76\u8005\u5011\u6703\u5b89\u6392\u4ed6\u5011\u9032\u884c 24 \u5c0f\u6642\u7684\u7761\u7720\u525d\u596a\uff0c\u5728\u8a66\u9a57\u7684 24 \u5c0f\u6642\u5167\u4e0d\u8b93\u4ed6\u5011\u7761\u89ba\u3002\u904e\u7a0b\u4e2d\u6703\u63a1\u96c6\u53c3\u8207\u8005\u5011\u7684\u8840\u6a23\u4ee5\u4e86\u89e3 A\u03b2 \u8207\u5176\u4ed6\u751f\u5316\u6578\u503c\u7684\u8b8a\u5316\u3002<\/p>\n\n\n<p>\u7d50\u679c\u767c\u73fe\u7761\u7720\u525d\u596a\u6703\u8b93\u8840\u4e2d\u7684 A\u03b2 \u986f\u8457\u589e\u52a0\uff0c\u800c\u4e14\u6297\u6c27\u5316\u7684\u9175\u7d20 SOD \u4e5f\u986f\u8457\u6e1b\u5c11\uff0c\u4e5f\u5c31\u662f\u8aaa\u77ed\u671f\u7684\u7761\u7720\u525d\u596a\u6703\u8b93\u53c3\u8207\u8005\u5011\u7684\u6c27\u5316\u58d3\u529b\u589e\u52a0\uff0c\u4e26\u5f71\u97ff A\u03b2 \u7684\u6e05\u9664\u3002<\/p>\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h2 id=\"%e6%be%b1%e7%b2%89%e6%a8%a3%e8%9b%8b%e7%99%bd%e8%88%87%e9%98%bf%e8%8c%b2%e6%b5%b7%e9%bb%98%e7%97%87\" class=\"wp-block-heading\">\u6fb1\u7c89\u6a23\u86cb\u767d\u8207\u963f\u8332\u6d77\u9ed8\u75c7<\/h2>\n\n\n<p>\u6fb1\u7c89\u6a23\u86cb\u767d\uff08amyloid-\u03b2\uff09\u662f\u7531 36\u201343 \u500b\u80fa\u57fa\u9178\u7d44\u6210\u7684\u80dc\u80bd\uff0c\u5728\u60a3\u6709 AD \u7684\u4eba\u8166\u4e2d\u6240\u767c\u73fe\u7684\u6fb1\u7c89\u6a23\u86cb\u767d\u6591\u584a\u7684\u4e3b\u8981\u6210\u4efd\u5c31\u662f A\u03b2\u3002<\/p>\n\n\n<p>A\u03b2 \u53c8\u662f\u5f9e\u54ea\u8dd1\u51fa\u4f86\u7684\u5462\uff1f<\/p>\n\n\n<p>\u5728\u8eab\u9ad4\u8a31\u591a\u7d44\u7e54\u7684\u819c\u88e1\u9762\u6709\u4e00\u7a2e\u53eb\u505a<a rel=\"noopener noreferrer\" href=\"https:\/\/www.wikiwand.com\/zh-tw\/%E5%89%8D%E9%A1%9E%E6%BE%B1%E7%B2%89%E8%9B%8B%E7%99%BD%E8%B3%AA\" target=\"_blank\">\u524d\u985e\u6fb1\u7c89\u86cb\u767d\u8cea<\/a>\uff08Amyloid precursor protein, \u7c21\u7a31 APP\uff09\uff0c\u7d93\u904e\u9175\u7d20\u4f5c\u7528\u5f8c\u5c31\u6703\u7522\u51fa A\u03b2\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5728\u795e\u7d93\u5143\u7a81\u89f8\u7684\u5730\u65b9 APP \u7279\u5225\u591a\uff0c\u56e0\u6b64\u672c\u4f86\u5c31\u6703\u6bd4\u8f03\u591a\u7684 A\u03b2 \u7522\u51fa\uff0c\u5b83\u5011\u5f88\u5bb9\u6613\u6703\u805a\u96c6\u5728\u4e00\u8d77\uff0c\u6709\u4e9b\u9577\u76f8\u6bd4\u8f03\u5947\u602a A\u03b2 \u7684\u6703\u5f71\u97ff\u5176\u4ed6 A\u03b2\uff0c\u8b93\u5b83\u5011\u4e5f\u8ddf\u8457\u9577\u5f97\u5947\u602a\uff0c\u805a\u96c6\u8d77\u4f86\u7684\u805a\u5408\u7269\uff08\u6fb1\u7c89\u6a23\u6591\u584a\uff09\u5c0d\u795e\u7d93\u7d30\u80de\u53ef\u662f\u6709\u6bd2\u6027\u7684\uff0c\u6700\u7d42\u53ef\u80fd\u5c0e\u81f4 AD\u3002<\/p>\n\n\n<p>\u6709\u4e86\u6fb1\u7c89\u6a23\u86cb\u767d\u8207 AD \u4e4b\u9593\u95dc\u4fc2\u7684\u8a8d\u77e5\u5f8c\uff0c\u518d\u56de\u904e\u982d\u4f86\u770b\u9019\u7bc7\u7814\u7a76\uff0c\u7f3a\u4e4f\u7761\u7720\u6703\u8b93\u8eab\u9ad4\u6e05\u9664 A\u03b2 \u7684\u80fd\u529b\u8b8a\u5dee\uff0c\u56e0\u800c\u7d2f\u7a4d\u5728\u7d44\u7e54\u589e\u52a0\u7f79\u60a3\u98a8\u96aa\u3002<\/p>\n\n\n<p>\u6240\u4ee5\uff0c\u53ef\u4ee5\u7684\u8a71\u65e9\u9ede\u7761\u5427\uff01\u53ea\u662f\u5be6\u969b\u4e0a\uff0c\u6709\u5f88\u591a\u4eba\u60f3\u597d\u597d\u7761\uff0c\u4f46\u771f\u8eba\u5728\u5e8a\u4e0a\u537b\u662f\u8f3e\u8f49\u96e3\u7720\uff0c\u9019\u6642\u5019\u8acb\u52d9\u5fc5\u597d\u597d\u7684\u5c0b\u6c42\u6cbb\u7642\uff0c\u4e0d\u7ba1\u662f\u5fc3\u7406\u9084\u662f\u751f\u7406\u56e0\u7d20\uff0c\u5118\u65e9\u6539\u5584\u5c0d\u4e4b\u5f8c\u7684\u751f\u6d3b\u54c1\u8cea\u90fd\u662f\u6703\u6709\u5e6b\u52a9\u7684\u3002<\/p>\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<h2 id=\"%e7%a0%94%e7%a9%b6%e7%9a%84%e8%a1%80%e6%b6%b2%e5%88%86%e6%9e%90%e9%a0%85%e7%9b%ae%ef%bc%9a\" class=\"wp-block-heading\">\u7814\u7a76\u7684\u8840\u6db2\u5206\u6790\u9805\u76ee\uff1a<\/h2>\n\n\n<ol><li>A\u03b242 \u548c A\u03b240\uff1a\u6fb1\u7c89\u6a23\u86cb\u767d\uff08A\u03b2\uff09\u5f8c\u9762\u7684\u6578\u5b57\u662f\u80fa\u57fa\u9178\u7684\u6578\u76ee\u3002<\/li><li>low-density lipoprotein receptor-related protein (sLRP-1)\uff1a\u5728\u7d30\u80de\u819c\u4e0a\u7684\u63a5\u53d7\u5668\uff0c\u53ef\u8abf\u7bc0\u7d30\u80de\u5167\u541e\u7684\u4f5c\u7528<\/li><li>soluble receptors for advanced glycation end products (sRAGE)\uff1a\u80fd\u8207<a href=\"https:\/\/nutrinote.co\/ages-in-foods-aging\/\" target=\"_blank\" aria-label=\"\u7cd6\u5316\u7d42\u7522\u7269 (opens in a new tab)\" rel=\"noreferrer noopener\" class=\"rank-math-link\">\u7cd6\u5316\u7d42\u7522\u7269<\/a>\u7d50\u5408\uff0c\u555f\u52d5\u767c\u708e\u53cd\u61c9<\/li><li>serum superoxide dismutase (SOD)\uff1a\u662f\u4e00\u7a2e\u6297\u6c27\u5316\u9175\u7d20<\/li><li>malondialdehyde (MDA)\uff1a\u8102\u8cea\u904e\u6c27\u5316\u7684\u6307\u6a19<\/li><\/ol>\n\n\n<p><\/p>\n\n\n\n\n\n<ol><li><a rel=\"noreferrer noopener\" href=\"http:\/\/content.iospress.com\/articles\/journal-of-alzheimers-disease\/jad161213\" target=\"_blank\">Wei, M., Zhao, B., Huo, K., Deng, Y., Shang, S., Liu, J.,\u00a0\u2026 &amp; Chen, C. (2017). Sleep Deprivation Induced Plasma Amyloid-\u03b2 Transport Disturbance in Healthy Young Adults. Journal of Alzheimer\u2019s Disease, (Preprint), 1\u20138.<\/a><\/li><li><a rel=\"noreferrer noopener\" href=\"https:\/\/www.wikiwand.com\/en\/Amyloid_beta\" target=\"_blank\">Amyloid beta\u200a\u2014\u200aWikipedia<\/a><\/li><\/ol>\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u60f3\u9810\u9632\u963f\u8332\u6d77\u9ed8\u75c7\u6709\u8a31\u591a\u7684\u4f5c\u6cd5\uff0c\u5176\u4e2d\u4e00\u9ede\u5f88\u91cd\u8981\u7684\u5c31\u662f\u8981\u64c1\u6709\u826f\u597d\u7684\u7761\u7720\u54c1\u8cea\uff0c\u56e0\u70ba\u7761\u4e0d\u597d\uff0c\u5927\u8166\u5c31\u6c92\u8fa6\u6cd5\u597d\u597d\u5730\u6e05\u9664\u5ee2\u7269\uff0c\u8ddf\u8457\u4e5f\u6703\u6709\u8f03\u591a\u7684 AGEs \u7522\u751f\u3002<\/p>\n","protected":false},"author":2,"featured_media":1356,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[77,76],"tags":[11,110,111,2],"powerkit_post_featured":[],"_links":{"self":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/345"}],"collection":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/comments?post=345"}],"version-history":[{"count":0,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/345\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/media\/1356"}],"wp:attachment":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/media?parent=345"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/categories?post=345"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/tags?post=345"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/powerkit_post_featured?post=345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}