{"id":281,"date":"2014-05-08T20:37:17","date_gmt":"2014-05-08T12:37:17","guid":{"rendered":"http:\/\/tre.tech.blog\/2014\/05\/08\/%e6%87%b7%e5%ad%95%e6%af%8d%e8%a6%aa%e7%9a%84%e9%a3%b2%e9%a3%9f%e8%83%bd%e5%bd%b1%e9%9f%bf%e5%ad%a9%e5%ad%90%e7%9a%84%e5%9f%ba%e5%9b%a0\/"},"modified":"2014-05-08T20:37:17","modified_gmt":"2014-05-08T12:37:17","slug":"%e6%87%b7%e5%ad%95%e6%af%8d%e8%a6%aa%e7%9a%84%e9%a3%b2%e9%a3%9f%e8%83%bd%e5%bd%b1%e9%9f%bf%e5%ad%a9%e5%ad%90%e7%9a%84%e5%9f%ba%e5%9b%a0","status":"publish","type":"post","link":"https:\/\/nutrinote.co\/%e6%87%b7%e5%ad%95%e6%af%8d%e8%a6%aa%e7%9a%84%e9%a3%b2%e9%a3%9f%e8%83%bd%e5%bd%b1%e9%9f%bf%e5%ad%a9%e5%ad%90%e7%9a%84%e5%9f%ba%e5%9b%a0\/","title":{"rendered":"\u61f7\u5b55\u6bcd\u89aa\u7684\u98f2\u98df\u80fd\u5f71\u97ff\u5b69\u5b50\u7684\u57fa\u56e0"},"content":{"rendered":"<figure class=\"wp-caption\">\n<img  decoding=\"async\"  data-width=\"5472\"  data-height=\"3648\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/cdn-images-1.medium.com\/max\/1200\/0*6TIUtmwrhUFqSOHq\" ><figcaption class=\"wp-caption-text\">Photo by <a href=\"https:\/\/unsplash.com\/@joshuaryanphoto?utm_source=medium&amp;utm_medium=referral\" target=\"_blank\" rel=\"noopener noreferrer\">Joshua Reddekopp<\/a> on\u00a0<a href=\"https:\/\/unsplash.com?utm_source=medium&amp;utm_medium=referral\" target=\"_blank\" rel=\"noopener noreferrer\">Unsplash<\/a><\/figcaption><\/figure>\n<p>\u300c\u61f7\u5b55\u7684\u6642\u5019\u53ef\u4ee5\u5403\u4ec0\u9ebc\u3001\u4e0d\u53ef\u4ee5\u5403\u4ec0\u9ebc\u300d\u662f\u61c9\u8a72\u662f\u8a31\u591a\u61f7\u5b55\u5973\u6027\u6703\u554f\u7684\u554f\u984c\u5427\uff01\u901a\u5e38\u5927\u591a\u662f\u5f9e\u6bcd\u89aa\u7684\u71df\u990a\u5145\u8db3\u5c31\u80fd\u4f9b\u61c9\u7d66\u80ce\u5152\u767c\u80b2\u7684\u89c0\u9ede\u4f86\u770b\u9019\u4ef6\u4e8b\u60c5\u3002\u4f46\u4e00\u7bc7\u767c\u8868\u5728 <a href=\"http:\/\/www.nature.com\/ncomms\/2014\/140429\/ncomms4746\/full\/ncomms4746.html\" target=\"_blank\" rel=\"noopener noreferrer\">Nature Communications<\/a> \u671f\u520a\u4e0a\u7684\u7814\u7a76\uff0c\u6216\u8a31\u80fd\u63d0\u4f9b\u4e00\u500b\u65b0\u7684\u89c0\u9ede\uff1a\u300c\u6bcd\u89aa\u7684\u98f2\u98df\u80fd\u5f71\u97ff\u5b69\u5b50\u7684\u57fa\u56e0\u300d\uff0c\u800c\u9019\u500b\u53ef\u80fd\u5f71\u97ff\u5b69\u5b50\u4e00\u8f29\u5b50\u3002<\/p>\n<pre>\u300c<a href=\"http:\/\/zh.wikipedia.org\/wiki\/%E8%A1%A8%E8%A7%80%E9%81%BA%E5%82%B3%E5%AD%B8\" target=\"_blank\" rel=\"noopener noreferrer\">\u8868\u89c0\u907a\u50b3\u5b78\uff08epigenetics\uff09<\/a>\u300d\u3002\u8868\u89c0\u907a\u50b3\u5b78\u53c8\u7a31\u300c\u64ec\u907a\u50b3\u5b78\u300d\u3001\u300c\u8868\u907a\u50b3\u5b78\u300d\u3001\u300c\u5916\u907a\u50b3\u5b78\u300d\u4ee5\u53ca\u300c\u5f8c\u907a\u50b3\u5b78\u300d\uff08\u82f1\u6587epigenetics\uff09\uff0c\u5728\u751f\u7269\u5b78\u548c\u7279\u5b9a\u7684\u907a\u50b3\u5b78\u9818\u57df\uff0c\u5176\u7814\u7a76\u7684\u662f\u5728\u4e0d\u6539\u8b8a DNA \u5e8f\u5217\u7684\u524d\u63d0\u4e0b\uff0c\u901a\u904e\u67d0\u4e9b\u6a5f\u5236\u5f15\u8d77\u53ef\u907a\u50b3\u7684\u57fa\u56e0\u8868\u9054\u6216\u7d30\u80de\u8868\u73fe\u578b\u7684\u8b8a\u5316\u3002<\/pre>\n<p>\u7814\u7a76\u7684\u8457\u773c\u9ede\u4e0d\u5728\u65bc\u5b69\u5b50\u5be6\u969b DNA\u5e8f\u5217\u7684\u8b8a\u5316\uff0c\u800c\u662f\u60f3\u89c0\u5bdf\u6bcd\u89aa\u7684\u98f2\u98df\u662f\u5426\u5177\u5f71\u97ff\u80ce\u5152\u5728\u8868\u89c0\u907a\u50b3\u4e0a\u7684\u6539\u8b8a\u3002<\/p>\n<h4 id=\"dna-%e7%94%b2%e5%9f%ba%e5%8c%96%ef%bc%88methylation%ef%bc%89\">DNA \u7532\u57fa\u5316\uff08methylation\uff09<\/h4>\n<p>DNA \u7532\u57fa\u5316\u662f\u4e00\u7a2e\u8868\u89c0\u907a\u50b3\u7684\u4fee\u98fe\u4f5c\u7528\uff0c\u5b83\u5728\u67d0\u500b DNA \u4f4d\u5143\u4e0a\u6dfb\u52a0\u7532\u57fa\uff08methyl group\uff09\u3002\u6211\u5011\u80fd\u5f9e\u98f2\u98df\u4e2d\u7684\u67d0\u7a2e\u98df\u7269\u7372\u53d6\u7532\u57fa\uff0c\u50cf\u662f\u542b\u6709<strong>\u81bd\u9e7c<\/strong>\u3001<strong>\u7dad\u751f\u7d20 B6<\/strong> \u8207 <strong>B12 <\/strong>\u7b49\u7dad\u751f\u7d20\u7684\u98df\u7269\u5c31\u662f\u826f\u597d\u7684\u7532\u57fa\u5718\u4f9b\u61c9\u6e90\u3002\uff08DNA \u7532\u57fa\u5316\u53ef\u80fd\u589e\u5f37\u67d0\u4e9b\u57fa\u56e0\u7684\u8868\u73fe\uff0c\u8b93\u500b\u9ad4\u5e36\u4f86\u66f4\u597d\u7684\u751f\u5b58\u80fd\u529b\uff0c\u4f46\u4e5f\u53ef\u80fd\u76f8\u53cd\u3002\uff09<\/p>\n<figure class=\"wp-caption\">\n<img  decoding=\"async\"  data-width=\"500\"  data-height=\"346\"  src=\"data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABAQMAAAAl21bKAAAAA1BMVEUAAP+KeNJXAAAAAXRSTlMAQObYZgAAAAlwSFlzAAAOxAAADsQBlSsOGwAAAApJREFUCNdjYAAAAAIAAeIhvDMAAAAASUVORK5CYII=\"  class=\" pk-lazyload\"  data-pk-sizes=\"auto\"  data-pk-src=\"https:\/\/cdn-images-1.medium.com\/max\/800\/1*S_J4TfTFnRZHHpaYWtVi9Q.jpeg\" ><figcaption class=\"wp-caption-text\">\u8868\u89c0\u907a\u50b3\u7684\u6a5f\u5236\u3002\u5716\u7247\u4f86\u6e90\uff1a<a href=\"http:\/\/zh.wikipedia.org\/wiki\/%E8%A1%A8%E8%A7%80%E9%81%BA%E5%82%B3%E5%AD%B8\" target=\"_blank\" rel=\"noopener noreferrer\">Wikipedia<\/a><\/figcaption><\/figure>\n<p>\u8a72\u7814\u7a76\u4ee5\u751f\u6d3b\u5728\u7518\u6bd4\u4e9e\u8fb2\u6751\u7684\u61f7\u5b55\u5973\u6027\u70ba\u5c0d\u8c61\u3002\u9078\u64c7\u4ed6\u5011\u7684\u539f\u56e0\u5728\u65bc\u4ed6\u5011\u7684\u98f2\u98df\u5927\u591a\u4f86\u81ea\u65bc\u81ea\u5df1\u8015\u4f5c\uff0c\u4e5f\u5c31\u80fd\u5403\u4ec0\u9ebc\u53ea\u80fd\u4f9d\u8cf4\u8001\u5929\u723a\u3002<\/p>\n<p>\u9084\u6709\u7518\u6bd4\u4e9e\u6709\u660e\u986f\u7684\u4e7e\u5b63\u548c\u96e8\u5b63\u4e4b\u5206\uff0c\u5728\u9019\u5169\u500b\u5b63\u7bc0\u88e1\u982d\uff0c\u4eba\u5011\u53ef\u4ee5\u7372\u53d6\u7684\u98df\u7269\uff0c\u5728\u71df\u990a\u54c1\u8cea\u4e0a\u6703\u6709\u5f88\u5927\u7684\u5dee\u7570\u3002\u56e0\u6b64\u7814\u7a76\u8005\u5011\u5c31\u60f3\u8fa6\u6cd5\u8aaa\u670d\u7576\u5730\u7684\u5973\u6027\uff0c\u5206\u5225\u5728\u4e7e\u5b63\u548c\u96e8\u5b63\u9032\u884c\u4f86\u9032\u884c\u7814\u7a76\uff0c84 \u4f4d\u5973\u6027\u5728\u96e8\u5b63\uff0c\u800c\u53e6\u5916 83 \u4f4d\u5973\u6027\u5728\u4e7e\u5b63\u9032\u884c\u3002<\/p>\n<p>\u7814\u7a76\u5718\u968a\u85c9\u7531\u8840\u6db2\u4f86\u6bd4\u5c0d\u6bcd\u89aa\u5011\u7684\u71df\u990a\u72c0\u6cc1\uff1a\u7279\u5225\u662f\u89c0\u5bdf\u90a3\u4e9b\u80fd\u63d0\u4f9b\u7532\u57fa\u5718\u71df\u990a\u7d20\uff0c\u9019\u4e9b\u7532\u57fa\u5718\u662f\u6709\u53ef\u80fd\u5f71\u97ff DNA \u4fee\u98fe\u7684\u3002<\/p>\n<p>\u4e4b\u5f8c\uff0c\u79d1\u5b78\u5bb6\u5011\u518d\u63a5\u8457\u8abf\u67e5\u5b69\u5b50\u5011\u7684 DNA\uff0c\u4ed6\u5011\u767c\u73fe\u5728\u96e8\u5b63\u9032\u884c\u7814\u7a76\u7684\u6bcd\u89aa\u5011\uff0c\u4ed6\u5011\u7684\u5b69\u5b50\u5728\u7814\u7a76\u4e2d\u6709\u6bd4\u5c0d\u7684\u57fa\u56e0\u88e1\uff0c\u7532\u57fa\u5316\u7684\u6bd4\u7387\u9ad8\u65bc\u4e7e\u5b63\u9032\u884c\u8a66\u9a57\u7684\u5b69\u5b50\u3002<\/p>\n<p>\u9019\u6a23\u7684\u7d50\u679c\u8207\u6bcd\u89aa\u7684\u71df\u990a\u72c0\u6cc1\u6709\u95dc\u3002\u6b64\u5916\uff0c\u7814\u7a76\u8005\u5011\u4e5f\u767c\u73fe\u6bcd\u89aa BMI \u7684\u589e\u52a0\u8207\u8f03\u4f4e\u6bd4\u7387\u7684\u65b0\u751f\u5152 DNA \u7532\u57fa\u5316\u6709\u95dc\u3002\uff08<strong>\u7c21\u55ae\u5730\u8aaa\u5c31\u662f\u8981\u98f2\u98df\u5747\u8861\uff0c\u7136\u5f8c\u5225\u5403\u592a\u80d6\u5c31\u5c0d\u4e86\u3002<\/strong>\uff09<\/p>\n<p>\u7814\u7a76\u767c\u73fe\u6bcd\u89aa\u7684\u98f2\u98df\u8207\u5b30\u5152 DNA \u7532\u57fa\u5316\u4e4b\u9593\u6709\u95dc\u4fc2\u662f\u76f8\u7576\u91cd\u8981\u7684\uff0c\u5118\u7ba1\u7814\u7a76\u6c92\u7e7c\u7e8c\u89c0\u5bdf\u9019\u4e9b\u57fa\u56e0\u4e0a\u7684\u8b8a\u5316\u5c0d\u5b69\u5b50\u7684\u5f71\u97ff\u3002\u96d6\u8aaa\u9019\u53ea\u662f\u521d\u6b65\u4e14\u4eba\u6578\u5c11\u7684\u7814\u7a76\uff0c\u4e0d\u904e\u7814\u7a76\u5718\u968a\u5011\u76f8\u4fe1\u9019\u4e9b\u8cc7\u6599\u5f88\u6709\u610f\u7fa9\uff0c\u5e0c\u671b\u80fd\u66f4\u9032\u4e00\u6b65\u7814\u7a76\u63a2\u67e5\u3002<\/p>\n<h4 id=\"%e8%a1%a8%e8%a7%80%e9%81%ba%e5%82%b3%e5%88%b0%e5%ba%95%e8%83%bd%e5%b9%b9%e5%98%9b%ef%bc%9f\">\u8868\u89c0\u907a\u50b3\u5230\u5e95\u80fd\u5e79\u561b\uff1f<\/h4>\n<p>\u6216\u8a31\u770b\u4e86\u524d\u9762\u7684\u5167\u5bb9\uff0c\u4f60\u6703\u60f3\u8457\u2026\u9019\u57fa\u56e0\u672c\u8eab\u7684\u5e8f\u5217\u6c92\u8b8a\uff0c\u4f46\u7d93\u904e\u4e00\u4e9b\u4fee\u98fe\u4f5c\u7528\u5f8c\u5e36\u4f86\u5916\u5728\u7684\u8b8a\u5316\uff0c\u90a3\u9ebc\uff0c\u7a76\u7adf\u662f\u8b8a\u4e86\u4e9b\u4ec0\u9ebc\u5462\uff1f<\/p>\n<p>\u76f8\u5c0d\u65bc\u50b3\u7d71\u7684\u907a\u50b3\u5b78\uff0c\u8868\u89c0\u907a\u50b3\u6bd4\u8f03\u80fd\u4ee3\u8868\u500b\u9ad4\u8207\u74b0\u5883\u4e4b\u9593\u76f8\u4e92\u5f71\u97ff\u5f8c\u7684\u7d50\u679c\u3002\u5c31\u4ee5\u62bd\u7159\u70ba\u4f8b\uff0c\u5b83\u672c\u8eab\u4e0d\u6703\u6539\u8b8a\u4f60\u7684 DNA \u5e8f\u5217\uff0c\u4f46\u6703\u7d66\u67d0\u4e9b\u90e8\u4f4d\u7684\u57fa\u56e0\u5e36\u4f86\u4e00\u4e9b\u4fee\u98fe\uff0c\u800c\u9019\u500b\u8b8a\u5316\u6703\u5ef6\u7e8c\u5230\u5f8c\u4ee3\uff0c\u5b69\u5b50\u51fa\u751f\u5f8c\u8eab\u9ad4\u5065\u5eb7\u72c0\u6cc1\u6703\u8b8a\u5f97\u6bd4\u8f03\u5dee\u3002\u6709\u4e9b\u7236\u6bcd\u64c1\u6709\u624d\u7684\u83ef\uff0c\u4e5f\u6709\u53ef\u80fd\u8b93\u5176\u5f8c\u4ee3\u7e7c\u627f\uff0c\u4e5f\u6709\u53ef\u80fd\u8207\u8868\u89c0\u907a\u50b3\u6709\u95dc\u4fc2\u3002<\/p>\n<p>\u8207\u5148\u5929\u7684 DNA \u5e8f\u5217\u8981\u6b77\u7d93\u9577\u4e45\u7684\u6f14\u5316\u624d\u6703\u6539\u8b8a\u4e0d\u540c\uff0c\u79d1\u5b78\u5bb6\u5011\u8a8d\u70ba\uff0c\u8868\u89c0\u907a\u50b3\u662f\u4e00\u7a2e\u77ed\u6642\u9593\u5167\u9069\u61c9\u74b0\u5883\u8b8a\u5316\u7684\u4e00\u7a2e\u907a\u50b3\u6a5f\u5236\uff0c\u5c0d\u751f\u7269\u500b\u9ad4\u7684\u751f\u5b58\u662f\u5f88\u91cd\u8981\u7684\u3002<\/p>\n<p>\u53e6\u5916\uff0c\u5e95\u4e0b\u7684\u53c3\u8003\u8cc7\u6599\u5167\u5bb9\u96d6\u7136\u6709\u9ede\u591a\uff0c\u4f46\u2026.\u6bd4\u672c\u7bc7\u7cbe\u91c7\u8036\uff01\uff08\u6c57\uff5e\uff09<\/p>\n<p><strong>\u53c3\u8003\u8cc7\u6599\u8207\u6587\u737b<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/www.nature.com\/ncomms\/2014\/140429\/ncomms4746\/full\/ncomms4746.html\" target=\"_blank\" rel=\"noopener noreferrer\">Dominguez-Salas, Paula et al. \u201cMaternal nutrition at conception modulates DNA methylation of human metastable epialleles.\u201d Nature communications 5 (2014).<\/a><\/li>\n<li><a href=\"http:\/\/zh.wikipedia.org\/wiki\/%E8%A1%A8%E8%A7%80%E9%81%BA%E5%82%B3%E5%AD%B8\" target=\"_blank\" rel=\"noopener noreferrer\">\u8868\u89c0\u907a\u50b3\u5b78\u200a\u2014\u200aWikipedia<\/a><\/li>\n<li><a href=\"http:\/\/cfh.com.tw\/HealthTopic\/%E5%BF%AB%E6%A8%82%E9%95%B7%E5%A3%BD\/%E7%94%9F%E6%B4%BB%E7%BF%92%E6%85%A3%E8%88%87%E5%A3%BD%E5%91%BD\/Aug--2012\/%E7%B0%A1%E4%BB%8B%EF%BC%9A%E8%A1%A8%E8%A7%80%E9%81%BA%E5%82%B3%E5%AD%B8.aspx\" target=\"_blank\" rel=\"noopener noreferrer\">CHF \u5065\u5eb7\u77e5\u8b58\u7db2\uff1a\u8868\u89c0\u907a\u50b3\u5b78<\/a><\/li>\n<li><a href=\"http:\/\/content.time.com\/time\/magazine\/article\/0,9171,1952313,00.html\" target=\"_blank\" rel=\"noopener noreferrer\">Time\u200a\u2014\u200aWhy Your DNA Isn\u2019t Your Destiny<\/a><\/li>\n<\/ul>\n<p><em>Originally published at www.nutrinote.co on May 8, 2014.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Photo by Joshua Reddekopp on\u00a0U&hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[7,14,23,22,2],"powerkit_post_featured":[],"_links":{"self":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/281"}],"collection":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/comments?post=281"}],"version-history":[{"count":0,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/posts\/281\/revisions"}],"wp:attachment":[{"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/media?parent=281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/categories?post=281"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/tags?post=281"},{"taxonomy":"powerkit_post_featured","embeddable":true,"href":"https:\/\/nutrinote.co\/wp-json\/wp\/v2\/powerkit_post_featured?post=281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}